human PKD2 Over-expression AAV

Cat. No: AAV-219022

Availability: 3-5 weeks

Name: AAV-h-PKD2

This is an AAV expressing Human PKD2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PKD2
Gene Name: polycystin 2, transient receptor potential cation channel
Gene ID: 5311
Gene Synonyms: APKD2; Pc-2; PC2; PKD4; TRPP2
ORF Size: 2907 bp
RefSeq#: BC112261
Gene Description: PKD2 encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.
UniGene ID: Hs.181272
HGNC ID: HGNC:9009