human PDLIM3 Over-expression AAV

Cat. No: AAV-218544

Availability: 3-5 weeks

Name: AAV-h-PDLIM3

This is an AAV expressing Human PDLIM3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PDLIM3
Gene Name: PDZ and LIM domain 3
Gene ID: 27295
Gene Synonyms: ALP
ORF Size: 951 bp
RefSeq#: BC027870
Gene Description: PDLIM3 contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.
UniGene ID: Hs.85862
HGNC ID: HGNC:20767