human PDK4 Over-expression AAV

Cat. No: AAV-218539

Availability: 3-5 weeks

Name: AAV-h-PDK4

This is an AAV expressing Human PDK4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PDK4
Gene Name: pyruvate dehydrogenase kinase 4
Gene ID: 5166
ORF Size: 1236 bp
RefSeq#: BC040239
Gene Description: PDK4 is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
UniGene ID: Hs.8364
HGNC ID: HGNC:8812