human PDE6H Over-expression AAV

Cat. No: AAV-218487

Availability: 3-5 weeks

Name: AAV-h-PDE6H

This is an AAV expressing Human PDE6H.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PDE6H
Gene Name: phosphodiesterase 6H
Gene ID: 5149
Gene Synonyms: ACHM6; RCD3
ORF Size: 252 bp
RefSeq#: BC093738
Gene Description: PDE6H encodes the inhibitory (or gamma) subunit of the cone-specific cGMP phosphodiesterase, which is a tetramer composed of two catalytic chains (alpha and beta), and two inhibitory chains (gamma). It is specifically expressed in the retina, and is involved in the transmission and amplification of the visual signal. Mutations in this gene are associated with retinal cone dystrophy type 3A (RCD3A).
UniGene ID: Hs.54471
HGNC ID: HGNC:8790