human PAX6 Over-expression AAV

Cat. No: AAV-218279

Availability: 3-5 weeks

Name: AAV-h-PAX6

This is an AAV expressing Human PAX6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PAX6
Gene Name: paired box 6
Gene ID: 5080
Gene Synonyms: AN; AN2; D11S812E; FVH1; MGDA; WAGR
ORF Size: 1269 bp
RefSeq#: BC011953
Gene Description: PAX6 encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. PAX6 is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
UniGene ID: Hs.716008
HGNC ID: HGNC:8620