human PAX2 Over-expression AAV

Cat. No: AAV-218270

Availability: 3-5 weeks

Name: AAV-h-PAX2

This is an AAV expressing Human PAX2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PAX2
Gene Name: paired box 2
Gene ID: 5076
Gene Synonyms: FSGS7; PAPRS
ORF Size: 1296 bp
RefSeq#: BC148710
Gene Description: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.
UniGene ID: Hs.155644
HGNC ID: HGNC:8616