human PAFAH1B3 Over-expression AAV

Cat. No: AAV-218130

Availability: 3-5 weeks

Name: AAV-h-PAFAH1B3

This is an AAV expressing Human PAFAH1B3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PAFAH1B3
Gene Name: platelet activating factor acetylhydrolase 1b catalytic subunit 3
Gene ID: 5050
Gene Synonyms: PAFAHG
ORF Size: 696 bp
RefSeq#: BC003016
Gene Description: PAFAH1B3 encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.
UniGene ID: Hs.466831
HGNC ID: HGNC:8576