human NPM1 Over-expression AAV

Cat. No: AAV-216983

Availability: 3-5 weeks

Name: AAV-h-NPM1

This is an AAV expressing Human NPM1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NPM1
Gene Name: nucleophosmin
Gene ID: 4869
Gene Synonyms: B23; NPM
ORF Size: 798 bp
RefSeq#: BC009623
Gene Description: NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.557550
HGNC ID: HGNC:7910