human NOP10 Over-expression AAV

Cat. No: AAV-216883

Availability: 3-5 weeks

Name: AAV-h-NOP10

This is an AAV expressing Human NOP10.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NOP10
Gene Name: NOP10 ribonucleoprotein
Gene ID: 55505
Gene Synonyms: DKCB1; NOLA3; NOP10P
ORF Size: 195 bp
RefSeq#: BC063023
Gene Description: NOP10 is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. NOP10 encodes a protein related to Saccharomyces cerevisiae Nop10p.
UniGene ID: Hs.14317
HGNC ID: HGNC:14378