human NNT Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-216846
Availability:
3-5 weeks
Name:
AAV-h-NNT
This is an AAV expressing Human NNT.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- NNT
- Gene Name
- nicotinamide nucleotide transhydrogenase
- Gene ID
- 23530
- Gene Synonyms
- GCCD4
- ORF Size
- 3261 bp
- RefSeq#
- BC110544
- Gene Description
- NNT encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.
- UniGene ID
- Hs.482043
- HGNC ID
- HGNC:7863
Related Products
Control Products
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