human MYL12B Over-expression AAV

Cat. No: AAV-216180

Availability: 3-5 weeks

Name: AAV-h-MYL12B

This is an AAV expressing Human MYL12B.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MYL12B
Gene Name: myosin light chain 12B
Gene ID: 103910
Gene Synonyms: MLC-B; MRLC2
ORF Size: 519 bp
RefSeq#: BC004994
Gene Description: The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 (PubMed 11942626)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.464472
HGNC ID: HGNC:29827