human MXI1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-216107
Availability:
3-5 weeks
Name:
AAV-h-MXI1
This is an AAV expressing Human MXI1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- MXI1
- Gene Name
- MAX interactor 1, dimerization protein
- Gene ID
- 4601
- Gene Synonyms
- bHLHc11; MAD2; MXD2; MXI
- ORF Size
- 888 bp
- RefSeq#
- BC035128
- Gene Description
- Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
- UniGene ID
- Hs.602078
- HGNC ID
- HGNC:7534
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