human MTMR3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-216018
Availability:
3-5 weeks
Name:
AAV-h-MTMR3
This is an AAV expressing Human MTMR3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- MTMR3
- Gene Name
- myotubularin related protein 3
- Gene ID
- 8897
- Gene Synonyms
- FYVE-DSP1; ZFYVE10
- ORF Size
- 3486 bp
- RefSeq#
- BC142713
- Gene Description
- MTMR3 encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.474536
- HGNC ID
- HGNC:7451
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