human MLXIPL Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-215543
Availability:
3-5 weeks
Name:
AAV-h-MLXIPL
This is an AAV expressing Human MLXIPL.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- MLXIPL
- Gene Name
- MLX interacting protein like
- Gene ID
- 51085
- Gene Synonyms
- bHLHd14; CHREBP; MIO; MLX; MONDOB; WBSCR14; WS-bHLH
- ORF Size
- 2166 bp
- RefSeq#
- BC012925
- Gene Description
- MLXIPL encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
- UniGene ID
- Hs.647055
- HGNC ID
- HGNC:12744
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