human MC3R Over-expression AAV

Cat. No: AAV-215135

Availability: 3-5 weeks

Name: AAV-h-MC3R

This is an AAV expressing Human MC3R.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MC3R
Gene Name: melanocortin 3 receptor
Gene ID: 4159
Gene Synonyms: BMIQ9; MC3; MC3-R; OB20; OQTL
ORF Size: 1083 bp
RefSeq#: BC098169
Gene Description: MC3R encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. MC3R maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
UniGene ID: Hs.248018
HGNC ID: HGNC:6931