human MAT1A Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-215062
Availability:
3-5 weeks
Name:
AAV-h-MAT1A
This is an AAV expressing Human MAT1A.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- MAT1A
- Gene Name
- methionine adenosyltransferase 1A
- Gene ID
- 4143
- Gene Synonyms
- MAT; MATA1; SAMS; SAMS1
- ORF Size
- 1188 bp
- RefSeq#
- BC018359
- Gene Description
- MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.
- UniGene ID
- Hs.282670
- HGNC ID
- HGNC:6903
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