human MARK4 Over-expression AAV

Cat. No: AAV-215039

Availability: 3-5 weeks

Name: AAV-h-MARK4

This is an AAV expressing Human MARK4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MARK4
Gene Name: microtubule affinity regulating kinase 4
Gene ID: 57787
Gene Synonyms: MARK4L; MARK4S; MARKL1; MARKL1L; PAR-1D
ORF Size: 2067 bp
RefSeq#: BC166620
Gene Description: MARK4 encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
UniGene ID: Hs.34314
HGNC ID: HGNC:13538