human LOC25845 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-214221
Availability:
3-5 weeks
Name:
AAV-h-LOC25845
This is an AAV expressing Human EXOC3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- EXOC3
- Gene Name
- exocyst complex component 3
- Gene ID
- 11336
- Gene Synonyms
- SEC6; SEC6L1; Sec6p
- ORF Size
- 2238 bp
- RefSeq#
- BC064569
- Gene Description
- EXOC3 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
- UniGene ID
- Hs.481464
- HGNC ID
- HGNC:30378
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