human LGALS3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-213851
Availability:
3-5 weeks
Name:
AAV-h-LGALS3
This is an AAV expressing Human LGALS3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- LGALS3
- Gene Name
- galectin 3
- Gene ID
- 3958
- Gene Synonyms
- CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2
- ORF Size
- 753 bp
- RefSeq#
- BC001120
- Gene Description
- LGALS3 encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
- UniGene ID
- Hs.531081
- HGNC ID
- HGNC:6563
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