human KRT75 Over-expression AAV

Cat. No: AAV-213449

Availability: 3-5 weeks

Name: AAV-h-KRT75

This is an AAV expressing Human KRT75.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KRT75
Gene Name: keratin 75
Gene ID: 9119
Gene Synonyms: K6HF; KB18; PFB
ORF Size: 1656 bp
RefSeq#: BC160175
Gene Description: KRT75 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. KRT75 is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS).
UniGene ID: Hs.697046
HGNC ID: HGNC:24431