human KIT Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-213154
Availability:
3-5 weeks
Name:
AAV-h-KIT
This is an AAV expressing Human KIT.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- KIT
- Gene Name
- KIT proto-oncogene receptor tyrosine kinase
- Gene ID
- 3815
- Gene Synonyms
- C-Kit; CD117; PBT; SCFR
- ORF Size
- 2931 bp
- RefSeq#
- BC071593
- Gene Description
- KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.479754
- HGNC ID
- HGNC:6342
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