human ING1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-212260
Availability:
3-5 weeks
Name:
AAV-h-ING1
This is an AAV expressing Human ING1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ING1
- Gene Name
- inhibitor of growth family member 1
- Gene ID
- 3621
- Gene Synonyms
- p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a
- ORF Size
- 840 bp
- RefSeq#
- BC093944
- Gene Description
- ING1 encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
- UniGene ID
- Hs.709738
- HGNC ID
- HGNC:6062
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