human IFNGR2 Over-expression AAV

Cat. No: AAV-211878

Availability: 3-5 weeks

Name: AAV-h-IFNGR2

This is an AAV expressing Human IFNGR2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IFNGR2
Gene Name: interferon gamma receptor 2 (interferon gamma transducer 1)
Gene ID: 3460
Gene Synonyms: AF-1; IFGR2; IFNGT1; IMD28
ORF Size: 1014 bp
RefSeq#: BC003624
Gene Description: IFNGR2 (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
UniGene ID: Hs.634632
HGNC ID: HGNC:5440