human IDS Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-211780
Availability:
3-5 weeks
Name:
AAV-h-IDS
This is an AAV expressing Human IDS.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- IDS
- Gene Name
- iduronate 2-sulfatase
- Gene ID
- 3423
- Gene Synonyms
- MPS2; SIDS
- ORF Size
- 939 bp
- RefSeq#
- BC006170
- Gene Description
- Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
- UniGene ID
- Hs.460960
- HGNC ID
- HGNC:5389
Related Products
Product | Cat No. |
---|---|
AAV-m-IDS | AAV-261859 |
Ad-h-IDS | ADV-211780 |
Ad-m-IDS | ADV-261859 |
AAV-h-IDS-shRNA | shAAV-211780 |
AAV-m-IDS-shRNA | shAAV-261859 |
Ad-h-IDS-shRNA | shADV-211780 |
Ad-m-IDS-shRNA | shADV-261859 |
Control Products
Vector Biolabs
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Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
Toll-free (US Only): 877-BIO-LABS
Fax: +1 215-525-1112
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