human IDI1 Over-expression AAV

Cat. No: AAV-211777

Availability: 3-5 weeks

Name: AAV-h-IDI1

This is an AAV expressing Human IDI1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IDI1
Gene Name: isopentenyl-diphosphate delta isomerase 1
Gene ID: 3422
Gene Synonyms: IPP1; IPPI1
ORF Size: 687 bp
RefSeq#: BC057827
Gene Description: IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.
UniGene ID: Hs.705849
HGNC ID: HGNC:5387