human IARS Over-expression AAV

Cat. No: AAV-211738

Availability: 3-5 weeks

Name: AAV-h-IARS

This is an AAV expressing Human IARS.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IARS
Gene Name: isoleucyl-tRNA synthetase
Gene ID: 3376
Gene Synonyms: GRIDHH; IARS1; ILERS; ILRS; IRS; PRO0785
ORF Size: 3168 bp
RefSeq#: BC065552
Gene Description: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
UniGene ID: Hs.445403
HGNC ID: HGNC:5330