human HSH2D Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-211611
Availability:
3-5 weeks
Name:
AAV-h-HSH2D
This is an AAV expressing Human HSH2D.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- HSH2D
- Gene Name
- hematopoietic SH2 domain containing
- Gene ID
- 84941
- Gene Synonyms
- ALX; HSH2
- ORF Size
- 1059 bp
- RefSeq#
- BC025237
- Gene Description
- T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 (PubMed 12960172)).(supplied by OMIM, Mar 2008)
- UniGene ID
- Hs.631617
- HGNC ID
- HGNC:24920
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