human HOXB5 Over-expression AAV

Cat. No: AAV-211457

Availability: 3-5 weeks

Name: AAV-h-HOXB5

This is an AAV expressing Human HOXB5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HOXB5
Gene Name: homeobox B5
Gene ID: 3215
Gene Synonyms: HHO.C10; HOX2; Hox2.1; HOX2A; HU-1
ORF Size: 810 bp
RefSeq#: BC117247
Gene Description: HOXB5 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.
UniGene ID: Hs.654456
HGNC ID: HGNC:5116