human HOOK1 Over-expression AAV

Cat. No: AAV-211424

Availability: 3-5 weeks

Name: AAV-h-HOOK1

This is an AAV expressing Human HOOK1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HOOK1
Gene Name: hook microtubule tethering protein 1
Gene ID: 51361
Gene Synonyms: HK1
ORF Size: 2187 bp
RefSeq#: BC011621
Gene Description: HOOK1 encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.
UniGene ID: Hs.378836
HGNC ID: HGNC:19884