human HDAC4 Over-expression AAV

Cat. No: AAV-210889

Availability: 3-5 weeks

Name: AAV-h-HDAC4

This is an AAV expressing Human HDAC4.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HDAC4
Gene Name: histone deacetylase 4
Gene ID: 9759
Gene Synonyms: AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA
ORF Size: 2919 bp
RefSeq#: BC039904
Gene Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
UniGene ID: Hs.688314
HGNC ID: HGNC:14063