human HDAC1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-210883
Availability:
3-5 weeks
Name:
AAV-h-HDAC1
This is an AAV expressing Human HDAC1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- HDAC1
- Gene Name
- histone deacetylase 1
- Gene ID
- 3065
- Gene Synonyms
- GON-10; HD1; RPD3; RPD3L1
- ORF Size
- 1449 bp
- RefSeq#
- BC000301
- Gene Description
- Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
- UniGene ID
- Hs.88556
- HGNC ID
- HGNC:4852
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