human GUCA2B Over-expression AAV

Cat. No: AAV-210682

Availability: 3-5 weeks

Name: AAV-h-GUCA2B

This is an AAV expressing Human GUCA2B.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GUCA2B
Gene Name: guanylate cyclase activator 2B
Gene ID: 2981
Gene Synonyms: GCAP-II; UGN
ORF Size: 339 bp
RefSeq#: BC093781
Gene Description: GUCA2B encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues.
UniGene ID: Hs.32966
HGNC ID: HGNC:4683