human GRIK1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-210514
Availability:
3-5 weeks
Name:
AAV-h-GRIK1
This is an AAV expressing Human GRIK1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GRIK1
- Gene Name
- glutamate ionotropic receptor kainate type subunit 1
- Gene ID
- 2897
- Gene Synonyms
- EAA3; EEA3; GLR5; GluK1; gluR-5; GLUR5
- ORF Size
- 2718 bp
- RefSeq#
- BC156975
- Gene Description
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene.
- UniGene ID
- Hs.706747
- HGNC ID
- HGNC:4579
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