human GPX4 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-210463
Availability:
Immediate
Name:
AAV-h-GPX4
This is an AAV expressing Human GPX4.
Request a Quote
Please enter your email address and we'll be in touch with more information:
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GPX4
- Gene Name
- glutathione peroxidase 4
- Gene ID
- 2879
- Gene Synonyms
- GPx-4; GSHPx-4; MCSP; PHGPx; SMDS; snGPx; snPHGPx
- ORF Size
- 594 bp
- RefSeq#
- BC022071
- Gene Description
- Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
- UniGene ID
- Hs.433951
- HGNC ID
- HGNC:4556
Related Products
Product | Cat No. |
---|---|
AAV-m-GPX4 | AAV-260717 |
Ad-h-GPX4 | ADV-210463 |
Ad-m-GPX4 | ADV-260717 |
AAV-h-GPX4-shRNA | shAAV-210463 |
AAV-m-GPX4-shRNA | shAAV-260717 |
Ad-h-GPX4-shRNA | shADV-210463 |
Ad-m-GPX4-shRNA | shADV-260717 |
Control Products
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
Toll-free (US Only): 877-BIO-LABS
Fax: +1 215-525-1112
Privacy Policy