human GPNMB Over-expression AAV

Cat. No: AAV-210248

Availability: 3-5 weeks

Name: AAV-h-GPNMB

This is an AAV expressing Human GPNMB.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GPNMB
Gene Name: glycoprotein nmb
Gene ID: 10457
Gene Synonyms: HGFIN; NMB
ORF Size: 1719 bp
RefSeq#: BC032783
Gene Description: GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.190495
HGNC ID: HGNC:4462