human GPHN Over-expression AAV

Cat. No: AAV-210232

Availability: 3-5 weeks

Name: AAV-h-GPHN

This is an AAV expressing Human GPHN.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GPHN
Gene Name: gephyrin
Gene ID: 10243
Gene Synonyms: GEPH; GPH; GPHRYN; HKPX1; MOCODC
ORF Size: 2310 bp
RefSeq#: BC030016
Gene Description: GPHN encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known.
UniGene ID: Hs.208765
HGNC ID: HGNC:15465