human GLRX Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-209995
Availability:
3-5 weeks
Name:
AAV-h-GLRX
This is an AAV expressing Human GLRX.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GLRX
- Gene Name
- glutaredoxin
- Gene ID
- 2745
- Gene Synonyms
- GRX; GRX1
- ORF Size
- 321 bp
- RefSeq#
- BC106075
- Gene Description
- GLRX encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
- UniGene ID
- Hs.712696
- HGNC ID
- HGNC:4330
Related Products
Product | Cat No. |
---|---|
AAV-m-GLRX | AAV-260203 |
Ad-h-GLRX | ADV-209995 |
Ad-m-GLRX | ADV-260203 |
AAV-h-GLRX-shRNA | shAAV-209995 |
AAV-m-GLRX-shRNA | shAAV-260203 |
Ad-h-GLRX-shRNA | shADV-209995 |
Ad-m-GLRX-shRNA | shADV-260203 |
Control Products
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
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Fax: +1 215-525-1112
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