human GCLM Over-expression AAV

Cat. No: AAV-209746

Availability: 3-5 weeks

Name: AAV-h-GCLM

This is an AAV expressing Human GCLM.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GCLM
Gene Name: glutamate-cysteine ligase modifier subunit
Gene ID: 2730
Gene Synonyms: GLCLR
ORF Size: 825 bp
RefSeq#: BC041809
Gene Description: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
UniGene ID: Hs.315562
HGNC ID: HGNC:4312