human GCKR Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-209743
Availability:
3-5 weeks
Name:
AAV-h-GCKR
This is an AAV expressing Human GCKR.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GCKR
- Gene Name
- glucokinase regulator
- Gene ID
- 2646
- Gene Synonyms
- FGQTL5; GKRP
- ORF Size
- 1878 bp
- RefSeq#
- BC130481
- Gene Description
- GCKR encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
- UniGene ID
- Hs.89771
- HGNC ID
- HGNC:4196
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