human GAB2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-209488
Availability:
3-5 weeks
Name:
AAV-h-GAB2
This is an AAV expressing Human GAB2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GAB2
- Gene Name
- GRB2 associated binding protein 2
- Gene ID
- 9846
- ORF Size
- 2031 bp
- RefSeq#
- BC131711
- Gene Description
- GAB2 is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
- UniGene ID
- Hs.429434
- HGNC ID
- HGNC:14458
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