human FUS Over-expression AAV

Cat. No: AAV-209408

Availability: 3-5 weeks

Name: AAV-h-FUS

This is an AAV expressing Human FUS.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FUS
Gene Name: FUS RNA binding protein
Gene ID: 2521
Gene Synonyms: ALS6; ETM4; FUS1; HNRNPP2; POMP75; TLS
ORF Size: 1581 bp
RefSeq#: BC000402
Gene Description: FUS encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
UniGene ID: Hs.513522
HGNC ID: HGNC:4010