human FN3KRP Over-expression AAV

Cat. No: AAV-209192

Availability: 3-5 weeks

Name: AAV-h-FN3KRP

This is an AAV expressing Human FN3KRP.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FN3KRP
Gene Name: fructosamine 3 kinase related protein
Gene ID: 79672
Gene Synonyms: FN3KL
ORF Size: 930 bp
RefSeq#: BC014408
Gene Description: A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.31431
HGNC ID: HGNC:25700