human FMR1 Over-expression AAV

Cat. No: AAV-209186

Availability: 3-5 weeks

Name: AAV-h-FMR1

This is an AAV expressing Human FMR1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FMR1
Gene Name: fragile X mental retardation 1
Gene ID: 2332
Gene Synonyms: FMRP; FRAXA; POF; POF1; POFX
ORF Size: 1761 bp
RefSeq#: BC086957
Gene Description: FMR1 binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
UniGene ID: Hs.103183
HGNC ID: HGNC:3775