human FKTN Over-expression AAV

Cat. No: AAV-209078

Availability: 3-5 weeks

Name: AAV-h-FKTN

This is an AAV expressing Human FKTN.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FKTN
Gene Name: fukutin
Gene ID: 2218
Gene Synonyms: CMD1X; FCMD; LGMD2M; MDDGA4; MDDGB4; MDDGC4
ORF Size: 990 bp
RefSeq#: BC117700
Gene Description: FKTN is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene.
UniGene ID: Hs.55777
HGNC ID: HGNC:3622