human FHL2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-209011
Availability:
3-5 weeks
Name:
AAV-h-FHL2
This is an AAV expressing Human FHL2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- FHL2
- Gene Name
- four and a half LIM domains 2
- Gene ID
- 2274
- Gene Synonyms
- AAG11; DRAL; FHL-2; SLIM-3; SLIM3
- ORF Size
- 840 bp
- RefSeq#
- BC014397
- Gene Description
- FHL2 encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.
- UniGene ID
- Hs.443687
- HGNC ID
- HGNC:3703
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