human FAP Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-208710
Availability:
Immediate
Name:
AAV-h-FAP
This is an AAV expressing Human FAP.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- FAP
- Gene Name
- fibroblast activation protein alpha
- Gene ID
- 2191
- Gene Synonyms
- DPPIV; FAPA; FAPalpha; SIMP
- ORF Size
- 2283 bp
- RefSeq#
- BC026250
- Gene Description
- FAP is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.
- UniGene ID
- Hs.654370
- HGNC ID
- HGNC:3590
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