human F2RL1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-208224
Availability:
3-5 weeks
Name:
AAV-h-F2RL1
This is an AAV expressing Human F2RL1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- F2RL1
- Gene Name
- F2R like trypsin receptor 1
- Gene ID
- 2150
- Gene Synonyms
- GPR11; PAR2
- ORF Size
- 1194 bp
- RefSeq#
- BC012453
- Gene Description
- Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
- UniGene ID
- Hs.154299
- HGNC ID
- HGNC:3538
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