human EZR Over-expression AAV

Cat. No: AAV-208213

Availability: 3-5 weeks

Name: AAV-h-EZR

This is an AAV expressing Human EZR.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EZR
Gene Name: ezrin
Gene ID: 7430
Gene Synonyms: CVIL; CVL; HEL-S-105; VIL2
ORF Size: 1761 bp
RefSeq#: BC013903
Gene Description: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
UniGene ID: Hs.487027
HGNC ID: HGNC:12691