human EPAS1 Over-expression AAV

Cat. No: AAV-207955

Availability: 3-5 weeks

Name: AAV-h-EPAS1

This is an AAV expressing Human EPAS1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EPAS1
Gene Name: endothelial PAS domain protein 1
Gene ID: 2034
Gene Synonyms: bHLHe73; ECYT4; HIF2A; HLF; MOP2; PASD2
ORF Size: 2613 bp
RefSeq#: BC051338
Gene Description: EPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.
UniGene ID: Hs.468410
HGNC ID: HGNC:3374