human EIF2S1 Over-expression AAV

Cat. No: AAV-207726

Availability: 3-5 weeks

Name: AAV-h-EIF2S1

This is an AAV expressing Human EIF2S1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EIF2S1
Gene Name: eukaryotic translation initiation factor 2 subunit alpha
Gene ID: 1965
Gene Synonyms: EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A
ORF Size: 948 bp
RefSeq#: BC002513
Gene Description: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 (PubMed 2948954)).(supplied by OMIM, Feb 2010)
UniGene ID: Hs.151777
HGNC ID: HGNC:3265